Evidence for PEM being unique to ME/CFS

  • I recently found this excellent article which summarises the research into patterns of exercise intolerance in various disease: https://www.healthrising.org/blog/2019/10/19/exercise-intolerance-chronic-fatigue-syndrome-unique/

    According to the evidence reviewed, the cardiovascular performance of people with ME/CFS demonstrates a unique pattern compared to other chronic diseases, and also demonstrates that exercise is genuinely harmful to us - with ME/CFS possibly being the only illness for which this is true 😮 I wish I could send a copy of this to every one of my doctors.

    I discovered this article while researching differences between multiple sclerosis and ME/CFS, as a few people (none of them doctors) have raised the possibility that I may have MS instead based on my symptoms being so heavily weighted towards neurological dysfunction. After reading this article, I think there is an approximately 0% chance I have anything other than ME/CFS. (Studies have shown that people with MS actually improve with exercise, with the exertion tolerance seen in MS apparently being mainly due to heat intolerance related to the rise in body temperature while exercising. For anyone interested, here is another article I read comparing MS and ME/CFS https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800741/)

  • @river So funny (not really) your comment about 0% chance of MS. You should be a GP, you seem to get answers more easily than many.

  • @river Thank you for posting this article, I will definitely have a read later today.

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