Oldies, but goodies – Older research articles



  • June 2020
    Epidemiological and clinical factors associated with post-exertional malaise severity in patients with myalgic encephalomyelitis/chronic fatigue syndrome
    Authors: Ghali A, Richa P, Lacout C, Gury A, Beucher AB, Homedan C, Lavigne C, Urbanski G (University Hospital, France)
    Link: https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-020-02419-4

    The authors in this study aimed to define possible factors that could be associated with the severity of post-exertional malaise (PEM). They discovered that PEM was more severe in patients that either had an age of onset > 32years, experienced recurrent infections during the course of their disease, or when their ME/CFS was caused by a gastrointestinal infectious event.

    These findings may prove useful for individualising disease management, specifically preventing PEM occurrences in patients that fall into one of these categories.


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